Focused Research Organization Portfolio
Scalable single-cell circuit mapping
E11 Bio aims to develop tools for understanding how the brain is wired in order to accelerate neuroscience and improve human health.
E11 Bio aims to develop a scalable technology pipeline to map the deep structural and molecular architecture of neural circuits spanning across entire mammalian brains.
Supported By:
Eric and Wendy Schmidt
Hearst Foundations
James Fickel
Riley & Susan Bechtel Foundation
Access the genetic potential of the biosphere
Cultivarium aims to make the world’s diverse microorganisms accessible for beneficial synthetic biology technologies.
Synthetic biology in non-model organisms; established to make the world’s diverse microorganisms accessible for use in beneficial synthetic biology technologies.
Supported By:
Eric and Wendy Schmidt
Scalable single-cell proteomics
PTI aims to quantify functional protein interactions and covariation that underpin health and disease.
PTI will develop proteomic technologies to scale protein analysis by over 100x to empower the exploration of proteome biology at unprecedented scale and resolution.
Supported By:
Eric and Wendy Schmidt
Ken Griffin
Mapping the pharmome
EvE Bio aims to identify every approved pharmaceutical drug's unintended/unknown molecular targets.
Elucidating drugs' off-target interactions to power drug repurposing, better drug design, and optimal training of artificial intelligence / machine learning systems for future drug development.
Supported By:
Eric and Wendy Schmidt
Lyda Hill Philanthropies
Founders Pledge
Interactive theorem proving and verification
Lean FRO aims to advance the formal mathematics revolution.
Revolutionizing mathematics by enabling mathematicians and other users to work seamlessly with, and have their work augmented by the Lean Proof Assistant: automated theorem proving and verification software.
Supported By:
Alfred P. Sloan Foundation
Simons Foundation International
Richard Merkin
Building next-generation brain-computer interfaces
Forest Neurotech aims to develop the first implanted whole-brain interface.
Developing a minimally invasive ultrasonic whole-brain computer interface to empower individuals and improve lives. Get in touch.
Supported By:
Eric and Wendy Schmidt
Griffin Catalyst
Riley & Susan Bechtel Foundation
James Fickel
Forensic immunology
IMPRINT aims to decode the language of the immune system to identify hidden causes of chronic disease.
Using machine learning and multiomics to retrospectively reconstruct disease course from memories stored in white blood cells, reducing the time to diagnosis and cure.
Supported By:
Peter Reinhardt
To be announced soon
Seed Stage Projects
Robust quantification of ocean-based carbon removal
[C]Worthy is a seed project building the tools needed to ensure safe, effective ocean-based carbon dioxide removal.
Supporting multi-scale oceanographic modeling and data integration for quantifying the efficacy and ecological impacts of ocean-based CDR.
Supported By:
Grantham Foundation
ClimateWorks Foundation
Founders Pledge
The Chan Zuckerberg Initiative
Environmental Defense Fund
Carbon to Sea Initiative
Stripe Climate